Growth Arrest Specific Gene 6 Protein Concentration in Cerebrospinal Fluid Correlates with Relapse Severity in Multiple Sclerosis

@inproceedings{Sainaghi2013GrowthAS,
  title={Growth Arrest Specific Gene 6 Protein Concentration in Cerebrospinal Fluid Correlates with Relapse Severity in Multiple Sclerosis},
  author={Pier Paolo Sainaghi and Laura Collimedaglia and Federica Alciato and Rosella Molinari and Daniele Sola and E. Ranza and Paola Naldi and Francesco Di Monaco and M A Leone and Mario Pirisi and Gian Carlo Avanzi},
  booktitle={Mediators of inflammation},
  year={2013}
}
BACKGROUND Growth arrest specific gene 6 (Gas6) protein enhances survival of oligodendrocytes and neurons, and it is involved in autoimmunity. Therefore, we aimed to verify whether cerebrospinal-fluid (CSF) Gas6 concentration may represent a biomarker of disease activity in multiple sclerosis. METHODS Sixty-five patients who underwent a spinal tap during… CONTINUE READING