Grouping solvents by statistical analysis of solvent property parameters: implication to polymorph screening.

Abstract

The success rate of discovering new polymorphs by crystallization from solution may be increased if solvents with diverse properties are used during initial polymorph screening. In this study, eight solvent parameters, including hydrogen bond acceptor propensity, hydrogen bond donor propensity, polarity/dipolarity, dipole moment, dielectric constant… (More)

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Cite this paper

@article{Gu2004GroupingSB, title={Grouping solvents by statistical analysis of solvent property parameters: implication to polymorph screening.}, author={Chong-Hui Gu and Hua Li and Rajesh B. Gandhi and Krishnaswamy S. Raghavan}, journal={International journal of pharmaceutics}, year={2004}, volume={283 1-2}, pages={117-25} }