Grouping patients for masseter muscle genotype-phenotype studies.

  title={Grouping patients for masseter muscle genotype-phenotype studies.},
  author={H. A. Moawad and A. Sinanan and M. Lewis and N. Hunt},
  journal={The Angle orthodontist},
  volume={82 2},
OBJECTIVES To use various facial classifications, including either/both vertical and horizontal facial criteria, to assess their effects on the interpretation of masseter muscle (MM) gene expression. MATERIALS AND METHODS Fresh MM biopsies were obtained from 29 patients (age, 16-36 years) with various facial phenotypes. Based on clinical and cephalometric analysis, patients were grouped using three different classifications: (1) basic vertical, (2) basic horizontal, and (3) combined vertical… Expand
Role of myosin 1H gene polymorphisms in mandibular retrognathism.
  • Richards M. Arun, B. V. Lakkakula, A. Chitharanjan
  • Biology, Medicine
  • American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
  • 2016
The results suggest that the rs3825393 polymorphism of the MYO1H gene is associated with an increased risk for mandibular retrognathism. Expand
Characterization of normal facial features and their association with genes
The variation in facial form and shape can be accurately quantified and visualized as a multidimensional statistical continuum with respect to the principal components. Expand
Genetic and epigenetic aspects of class III malocclusion with mandibular prognathism phenotypes
Genetic studies on the genetic mechanisms of facial variations show signs of future success in helping to understand the etiology of malocclusion and variation of dentofacial morphology, which gives helpful insights on the limits of what orthodontic treatments could achieve. Expand


Myosin proteins identified from masseter muscle using quantitative reverse transcriptase-polymerase chain reaction--a pilot study of the relevance to orthodontics.
The results showed that there were distinct differences in gene expression between patients with a wide range of variation although changes in MYH1 were consistent with one cephalometric variable, the maxillo-mandibular angle. Expand
Myosin heavy chain protein and gene expression in the masseter muscle of adult patients with distal or mesial malocclusion.
The anterior part of the masseter muscle from patients with distal occlusion contained more type 1 and 2x MyHC mRNA, as compared to patients with mesial occlusions (P < 0.05), which may be caused by the enforced stress of the masticatory muscle in distal Occlusion because of the disadvantageous pivot. Expand
Masseter muscle adaptation following surgical correction of vertical maxillary excess.
  • S. Boyd, W. Gonyea, H. Legan, W. Bell
  • Medicine
  • Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • 1989
The results of this study indicate that the human masseter responds to surgical manipulation of the jaws in a histochemically demonstrable manner, with the nature and magnitude of the response associated with the particular surgical procedure(s) performed. Expand
[Classification of skeletal facial types].
  • V. Sassouni
  • Medicine
  • Rivista italiana di stomatologia
  • 1977
This classification of facial types may be used to distinguish skeletal from dental malocclusion, to evaluate physiologic differences, to explain variation in facial esthetics, to describe racial differences in facial proportions, to study hereditary transmission, and to predict facial growth. Expand
Change of mRNA amount of myosin heavy chain in masseter muscle after orthognathic surgery of patients with malocclusion.
  • T. Gedrange, C. Büttner, +4 authors W. Harzer
  • Medicine
  • Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • 2006
Patients should use the postoperative interval for training their masticatory muscles to improve the stability of treatment result and prevents relapse. Expand
Indices of extracellular matrix turnover in human masseter muscles as markers of craniofacial form--a preliminary study.
Preliminary data indicate that in most individuals, an excess of TIMP-1, compared with MMP-2 and M MP-9, limits ECM turnover in human masseter muscle, and does not confirm that indices ofECM turnover are a reflection of an individual's vertical facial form. Expand
Histochemical fibre-type profile in the human masseter muscle
It is concluded that the masseter muscle in normal human subjects has a very special fibre composition, with ATPase-IM fibres being a part of the normal fibre population. Expand
Class II malocclusion with maxillary protrusion from the deciduous through the mixed dentition: a longitudinal study.
The results indicate that a Class II skeletal pattern due to a maxillary protrusion is established early in the deciduous dentition and remains unmodified in the transition to the mixed dentition. Expand
The long face syndrome: vertical maxillary excess.
It is confirmed that this basic dentofacial deformity is associated with excessive vertical growth of the maxilla and an increased mandibular ramus height isassociated with the closed-bite group. Expand
A Manual of Facial Growth: A Computer Analysis of Longitudinal Cephalometric Growth Data
The increased use of sophisticated orthodontic appliances for the correction of misplaced teeth has increased the need for precise information about facial growth. This book reviews data on a largeExpand