Group II self-splicing introns in bacteria

  title={Group II self-splicing introns in bacteria},
  author={J L Ferat and François Michel},
LIKE nuclear premessenger introns, group II self-splicing introns are excised from primary transcripts as branched molecules, containing a 2′–5′ phosphodiester bond. For this reason, it is widely believed that the ribozyme (catalytic RNA) core of group II introns, or some evolutionarily related molecule, gave rise to the RNA components of the spliceosomal splicing machinery of the eukaryotic nucleus1. One difficulty with this hypothesis has been the restricted distribution of group II introns… CONTINUE READING