Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.

@article{Blumer2012GroupIA,
  title={Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.},
  author={J B Blumer and Sukru Sadik Oner and Stephen M. Lanier},
  journal={Acta physiologica},
  year={2012},
  volume={204 2},
  pages={202-18}
}
Beyond the core triad of receptor, Gαβγ and effector, there are multiple accessory proteins that provide alternative modes of signal input and regulatory adaptability to G-protein signalling systems. Such accessory proteins may segregate a signalling complex to microdomains of the cell, regulate the basal activity, efficiency and specificity of signal propagation and/or serve as alternative binding partners for Gα or Gβγ independent of the classical heterotrimeric Gαβγ complex. The latter… CONTINUE READING

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