Group I mGluRs increase locomotor network excitability in Xenopus tadpoles via presynaptic inhibition of glycinergic neurotransmission.

@article{Chapman2008GroupIM,
  title={Group I mGluRs increase locomotor network excitability in Xenopus tadpoles via presynaptic inhibition of glycinergic neurotransmission.},
  author={Rebecca J. Chapman and Jonathan P Issberner and Keith T Sillar},
  journal={The European journal of neuroscience},
  year={2008},
  volume={28 5},
  pages={903-13}
}
The group I metabotropic glutamate receptor agonist (S)-3,5-dihyroxyphenylglycine (DHPG) increases the frequency of rhythmic swimming activity in Xenopus tadpoles. This study explores the possibility that group I receptor modulation occurs in part via depression of inhibitory synaptic transmission. Applications of the glycine receptor antagonist strychnine… CONTINUE READING