Group B streptococcal conjugate vaccines.

  title={Group B streptococcal conjugate vaccines.},
  author={Carol J. Baker and Morven S. Edwards},
  journal={Archives of disease in childhood},
  volume={88 5},
Linkage of bacterial capsular polysaccharides to proteins to create conjugate vaccines has had a dramatic impact on the health of children. Although unconjugated polysaccharides are poorly immunogenic in infants and some older children and adults, their covalent coupling with proteins stimulates T cell dependent antigenic recognition that profoundly enhances immunogenicity. In the decade since the introduction and widespread use of Haemophilus influenzae type b polysaccharide conjugate vaccines… CONTINUE READING


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