Group A streptococcal vaccines: paving a path for accelerated development.


Group A streptococci (GAS) are important causes of morbidity and mortality worldwide. These organisms cause a wide spectrum of disease, ranging from uncomplicated sore throat to invasive, life-threatening infections, as well as immune complications such as acute rheumatic fever (ARF), rheumatic heart disease (RHD) and acute post-streptococcal… (More)
DOI: 10.1016/j.vaccine.2012.09.045