• DOI:10.1038/s41385-020-0298-2
Corpus ID: 218898687

Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11

@article{Panova2020Group2IL,
  title={Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11},
  author={V. Panova and Mayuri Gogoi and No{\'e} Rodr{\'i}guez-Rodr{\'i}guez and M. Sivasubramaniam and H. Jolin and Morgan W. D. Heycock and J. A. Walker and Batika M. J. Rana and L. Drynan and Michael R G Hodskinson and R. Pannell and G. King and M. Wing and A. Easton and C. Oedekoven and D. Kent and P. Fallon and J. Barlow and A. McKenzie},
  journal={Mucosal Immunology},
  year={2020},
  volume={14},
  pages={26 - 37}
}

• V. Panova, Mayuri Gogoi, +16 authors A. McKenzie
• Published 2020
• Chemistry, Medicine
• Mucosal Immunology

Type-2 immunity is characterised by interleukin (IL)-4, IL-5 and IL-13, eosinophilia, mucus production, IgE, and alternatively activated macrophages (AAM). However, despite the lack of neutrophil chemoattractants such as CXCL1, neutrophils, a feature of type-1 immunity, are observed in type-2 responses. Consequently, alternative mechanisms must exist to ensure that neutrophils can contribute to type-2 immune reactions without escalation of deleterious inflammation. We now demonstrate that type… Expand

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