Ground-glass hepatocytes in unselected liver biopsies. ultrastructure and relationship to hepatitis B surface antigen.

@article{Winckler1976GroundglassHI,
  title={Ground-glass hepatocytes in unselected liver biopsies. ultrastructure and relationship to hepatitis B surface antigen.},
  author={Karoline Winckler and Ulrich Junge and Werner O. C. Creutzfeldt},
  journal={Scandinavian journal of gastroenterology},
  year={1976},
  volume={11 2},
  pages={
          167-70
        }
}
400 unselected liver biopsies were stained with aldehyde-thionin (AT) and examined for ground-glass hepatocytes (GGH). 1) AT-positive GGH were found in about half of all HBSAg-positive patients but were never seen in HBSAg-negative patients. 2) AT-positive GGH were observed in healthy HBSAg carriers and in all forms of chronic hepatitis but never in acute HBSAg-positive hepatitis. 3) AT-negative GGH were occasionally seen in HBSAg-negative patients under drug treatment. 4) Ultrastructurally GGH… CONTINUE READING

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