Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 Å Resolution*

  title={Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 Å Resolution*},
  author={Matthew W. Bowler and Martin G. Montgomery and Andrew G W Leslie and John E. Walker},
  journal={Journal of Biological Chemistry},
  pages={14238 - 14242}
The structure of bovine F1-ATPase, crystallized in the presence of AMP-PNP and ADP, but in the absence of azide, has been determined at 1.9Å resolution. This structure has been compared with the previously described structure of bovine F1-ATPase determined at 1.95Å resolution with crystals grown under the same conditions but in the presence of azide. The two structures are extremely similar, but they differ in the nucleotides that are bound to the catalytic site in the βDP-subunit. In the… 

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