Grey matter pathology in multiple sclerosis

@article{Geurts2008GreyMP,
  title={Grey matter pathology in multiple sclerosis},
  author={Jeroen J. G. Geurts and Frederik Barkhof},
  journal={The Lancet Neurology},
  year={2008},
  volume={7},
  pages={841-851}
}
Multiple sclerosis (MS) has been classically regarded as a white matter disease. However, recent histopathological studies have convincingly shown that grey matter regions are also heavily affected. Grey matter damage starts early in the disease and substantially affects clinico-cognitive functioning. Detection of cortical grey matter lesions by use of standard MRI techniques has proved challenging, and more advanced techniques are needed. At present, the causes of grey matter damage are… CONTINUE READING
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