Grey matter morphological anomalies in the caudate head in first-episode psychosis patients with delusions of reference

  title={Grey matter morphological anomalies in the caudate head in first-episode psychosis patients with delusions of reference},
  author={Haojuan Tao and Gloria Hoi Yan Wong and Huiran Zhang and Yuan Zhou and Zhimin Xue and Baoci Shan and Eric Yu-Hai Chen and Zhening Liu},
  journal={Psychiatry Research: Neuroimaging},

Decreased Left Putamen and Thalamus Volume Correlates with Delusions in First-Episode Schizophrenia Patients

Left putamen and thalamus volume loss may be biological correlates of delusions in schizophrenia and inter-group differences in gray matter volume are explored.

Gray matter morphological anomalies in the cerebellar vermis in first-episode schizophrenia patients with cognitive deficits

Decreased gray matter density in the vermis and tonsil of cerebellum may underlie early psychosis and serve as a candidate biomarker for schizophrenia with cognitive deficits.


The finding of the dependence of the intensity of psychotic manifestations on the perimeter of the right caudate head and not on its area speaks in favor of the caudates head surface deformations as one of the markers of intensity of psychosis manifestations in patients with schizophrenia.

Systems Neuroscience of Psychosis: Mapping Schizophrenia Symptoms onto Brain Systems

The results of several empirical studies support the hypothesis that the proposed three-dimensional symptom structure, segregated into the affective, the language, and the motor domain, can be specifically mapped onto structural and functional abnormalities of the respective brain systems.

Dysconnectivity of the Agency Network in Schizophrenia: A Functional Magnetic Resonance Imaging Study

Dysconnectivity of the agency network in schizophrenia may lead to self-disturbance through deficits in associative learning of SoA, and these findings may explain why pathological function of the striatum in schizophrenia leads toSelf- Disturbance.

Frontolimbic affective bias and false narratives from brain disease.

Altered Temporal Variability of Local and Large-Scale Resting-State Brain Functional Connectivity Patterns in Schizophrenia and Bipolar Disorder

More widespread changes were found in the schizophrenia group, involving increased FC variabilities in sensorimotor, visual, attention, limbic and subcortical areas at both regional and network levels, as well as decreased regional FC Variabilities in the default-mode areas.

Taxonomizing the Neural Correlates of Delusion

Current evidence for the neurobiological mechanism of delusions is reviewed, with special focus on persecutory delusions and delusions of reference, which represent two of the more commonly accepted subtypes.

Bridging Structural MRI with Cognitive Function for Individual Level Classification of Early Psychosis via Deep Learning

Recent efforts have been made to apply machine learning and deep learning approaches to the automated classification of schizophrenia using structural magnetic resonance imaging (sMRI) at the



Ventral striatum gray matter density reduction in patients with schizophrenia and psychotic emotional dysregulation☆

Cerebral grey, white matter and csf in never-medicated, first-episode schizophrenia

Brain volume changes in first-episode schizophrenia: a 1-year follow-up study.

The loss of global gray matter in schizophrenia is progressive, occurs at an early stage of the illness, and is related to the disease process and antipsychotic medication.

Early striatal hypertrophy in first-episode psychosis within 3 weeks of initiating antipsychotic drug treatment

Early striatal grey-matter enlargement may occur within the first 3–4 weeks of antipsychotic treatment, possible reasons for putative striatal hypertrophy and its implications are discussed.

Fusiform gyrus volume reduction in first-episode schizophrenia: a magnetic resonance imaging study.

Schizophrenia is associated with a bilateral reduction in fusiform gyrus gray matter volume that is evident at the time of first hospitalization and is different from the presentation of affective psychosis.

Brain volume in first-episode schizophrenia

Average volumetric changes are close to the limit of detection by MRI methods, indicating whether schizophrenia is a neurodegenerative process that begins at about the time of symptom onset, or whether it is better characterised as a neurodevelopmental process that produces abnormal brain volumes at an early age.

Brain morphology in antipsychotic-naïve schizophrenia: A study of multiple brain structures

The findings suggest that some brain abnormalities are present in the early stages of schizophrenia and suggests that brain abnormalities reported in patients with chronic schizophrenia develop in a later stage of the disease and/or are medication induced.

Morphometric brain abnormalities in schizophrenia in a population-based sample: relationship to duration of illness.

Gray and white matter deficits were associated with duration of illness suggesting either that developmental brain deficits relate to an earlier age of onset or that brain abnormalities in schizophrenia are progressive in nature.