Grey matter damage predicts the evolution of primary progressive multiple sclerosis at 5 years.

@article{Rovaris2006GreyMD,
  title={Grey matter damage predicts the evolution of primary progressive multiple sclerosis at 5 years.},
  author={Marco Rovaris and Elda Judica and Antonio Gallo and Beatrice Benedetti and Maria Pia Sormani and Domenico Caputo and Angelo Ghezzi and Enrico Montanari and Antonio Bertolotto and Gianluigi Mancardi and Roberto Bergamaschi and Vittorio Martinelli and Giancarlo Comi and Massimo Filippi},
  journal={Brain : a journal of neurology},
  year={2006},
  volume={129 Pt 10},
  pages={2628-34}
}
Reliable prognostic markers of primary progressive (PP) multiple sclerosis evolution are still needed. Diffusion tensor (DT) MRI can quantify normal-appearing white matter (NAWM) and grey matter (GM) damage in multiple sclerosis patients. We investigated whether conventional and DT-MRI-derived measures can predict the long-term clinical evolution of PP multiple sclerosis. In 54 PP multiple sclerosis patients, conventional and DT-MRI scans of the brain and T1-weighted scans of the cervical cord… CONTINUE READING

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