Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia.

@article{Aoyama2011GreyMA,
  title={Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia.},
  author={Naoko Aoyama and Jean Th{\'e}berge and Dick J. Drost and R Ahul Manchanda and Sandra Northcott and Richard W. J. Neufeld and Ravi S. Menon and Nagalingam Rajakumar and William Pavlosky and Maria Densmore and Betsy Schaefer and Peter C. Williamson},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2011},
  volume={198 6},
  pages={
          448-56
        }
}
BACKGROUND Thalamic glutamine loss and grey matter reduction suggest neurodegeneration in first-episode schizophrenia, but the duration is unknown. AIMS To observe glutamine and glutamate levels, grey matter volumes and social functioning in patients with schizophrenia followed to 80 months after diagnosis. METHOD Grey matter volumes and proton magnetic resonance spectroscopy metabolites in left anterior cingulate and left thalamus were measured in 17 patients with schizophrenia before… CONTINUE READING
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