Grey and white matter atrophy in early clinical stages of primary progressive multiple sclerosis

@article{SastreGarriga2004GreyAW,
  title={Grey and white matter atrophy in early clinical stages of primary progressive multiple sclerosis},
  author={Jaume Sastre-Garriga and Gordon T Ingle and Declan T. Chard and Llu{\'i}s Rami{\'o}-Torrent{\`a} and David H. Miller and Alan J. Thompson},
  journal={NeuroImage},
  year={2004},
  volume={22},
  pages={353-359}
}
BACKGROUND There is little information available on grey and white matter (GM and WM) atrophy in primary progressive multiple sclerosis (PPMS) and on their relationships with clinical and other magnetic resonance imaging (MRI) measures. AIM To evaluate disease progression in the early phase of PPMS, focusing on axonal loss as assessed by volumetric MRI measures of WM and GM, and to determine their relationships with clinical outcomes and lesion load measures. METHODS Forty-three patients… CONTINUE READING

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