Green tea polyphenol epigallocatechin-3-gallate inhibits the expression of nitric oxide synthase and generation of nitric oxide induced by ultraviolet B in HaCaT cells.

@article{Song2006GreenTP,
  title={Green tea polyphenol epigallocatechin-3-gallate inhibits the expression of nitric oxide synthase and generation of nitric oxide induced by ultraviolet B in HaCaT cells.},
  author={Xiu-zu Song and Z. Bi and Ai-e Xu},
  journal={Chinese medical journal},
  year={2006},
  volume={119 4},
  pages={
          282-7
        }
}
BACKGROUND Nitic oxide (NO) has been implicated in the pathogenesis of various inflammatory diseases, including sunburn and pigmentation induced by ultraviolet irradiation. Epigallocatechin-3-gallate (EGCG) is the major effective component in green tea and can protect skin from ultraviolet-induced damage. The purpose of this study was to investigate the protective mechanisms of EGCG on inducible nitric oxide synthase (iNOS) expression and NO generation by ultraviolet B (UVB) irradiation in… Expand
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Epigallocatechin-3-Gallate Inhibits Secretion of TNF-α, IL-6 and IL-8 through the Attenuation of ERK and NF-κB in HMC-1 Cells
  • Hye-Young Shin, Sang-Hyun Kim, +5 authors Hyung-Min Kim
  • Biology
  • International Archives of Allergy and Immunology
  • 2006
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