Green tea extract protects rats against myocardial infarction associated with left anterior descending coronary artery ligation

@article{Hsieh2009GreenTE,
  title={Green tea extract protects rats against myocardial infarction associated with left anterior descending coronary artery ligation},
  author={S P Hsieh and Dan-Chin Tsai and Jan-Yow Chen and Sen-Wei Tsai and Y. Liou},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2009},
  volume={458},
  pages={631-642}
}
There is increasing evidence that green tea polyphenols can protect against myocardial damage. Recently, we showed that they bind to cardiac troponin C and alter myofilament Ca2+ sensitivity in cardiac muscle. In the present study, we examined whether green tea extract (GTE) could prevent the progressive remodeling seen in ischemic myocardium and improve cardiac function by modulation of the contractile apparatus utilizing a myocardial infarction (MI) model in the rat involving ligation of the… CONTINUE READING
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