Green tea extract, epigallocatechin-3-gallate, inhibits the growth and invasive ability of human glioma cells.

  title={Green tea extract, epigallocatechin-3-gallate, inhibits the growth and invasive ability of human glioma cells.},
  author={Wei Zhang and Jianping Jia},
  journal={Molecular medicine reports},
  volume={1 5},
  • Wei ZhangJ. Jia
  • Published 1 September 2008
  • Biology, Medicine
  • Molecular medicine reports
Epigallocatechin-3-gallate (EGCG) is a major constituent of green tea, but its effects on glioma cell growth have not been reported. The aim of this study was to investigate the anticancer effect of EGCG on the growth and invasive ability of glioma cells, as well as the molecular mechanisms responsible for it. Two glioma cell lines were treated with EGCG, and its effect on cell proliferation and invasive ability was studied using the MTT, Matrigel invasion and 3-D collagen colony forming assays… 
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