Green tea epigallocatechin-3-gallate (EGCG) and other flavonoids reduce Alzheimer's amyloid-induced mitochondrial dysfunction.

@article{Dragievi2011GreenTE,
  title={Green tea epigallocatechin-3-gallate (EGCG) and other flavonoids reduce Alzheimer's amyloid-induced mitochondrial dysfunction.},
  author={N. Dragi{\vc}evi{\'c} and A. Smith and X. Lin and Fang Yuan and Neil Copes and V. Delic and J. Tan and C. Cao and R. D. Shytle and P. Bradshaw},
  journal={Journal of Alzheimer's disease : JAD},
  year={2011},
  volume={26 3},
  pages={
          507-21
        }
}
Amyloid-β (Aβ)-induced mitochondrial dysfunction may play a role in the onset and progression of Alzheimer's disease (AD). Therefore, therapeutics targeted to improve mitochondrial function could be beneficial. Plant-derived flavonoids have shown promise in improving certain AD phenotypes, but the overall mechanism of action(s) through which flavonoids protect from AD is still unknown. To identify flavonoids and other natural products that may correct amyloid-induced mitochondrial dysfunction… Expand
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