Green tea catechin polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia.

@article{Burckhardt2008GreenTC,
  title={Green tea catechin polyphenols attenuate behavioral and oxidative responses to intermittent hypoxia.},
  author={Isabel C Burckhardt and David Gozal and Ehab A. Dayyat and Yu Cheng and Richard Changxun Li and Aviv D Goldbart and Barry W. Row},
  journal={American journal of respiratory and critical care medicine},
  year={2008},
  volume={177 10},
  pages={1135-41}
}
RATIONALE The intermittent hypoxia (IH) that characterizes sleep-disordered breathing impairs spatial learning and increases NADPH oxidase activity and oxidative stress in rodents. We hypothesized that green tea catechin polyphenols (GTPs) may attenuate IH-induced neurobehavioral deficits by reducing IH-induced NADPH oxidase expression, lipid peroxidation, and inflammation. OBJECTIVES To assess the effects of GTP administered in drinking water on the cognitive, inflammatory, and oxidative… CONTINUE READING