Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications.

@article{Singh2011GreenTC,
  title={Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications.},
  author={Brahma Nand Singh and Sharmila Shankar and Rakesh K Srivastava},
  journal={Biochemical pharmacology},
  year={2011},
  volume={82 12},
  pages={1807-21}
}
An expanding body of preclinical evidence suggests EGCG, the major catechin found in green tea (Camellia sinensis), has the potential to impact a variety of human diseases. Apparently, EGCG functions as a powerful antioxidant, preventing oxidative damage in healthy cells, but also as an antiangiogenic and antitumor agent and as a modulator of tumor cell response to chemotherapy. Much of the cancer chemopreventive properties of green tea are mediated by EGCG that induces apoptosis and promotes… CONTINUE READING
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