Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1).

Abstract

Urinary KIM-1 is an ideal biomarker for acute kidney injury diagnosis. The proof-of-concept is demonstrated by utilizing the hydroxyapatite derived from natural fish scales as an electrode material, where the sensing of KIM-1 is shown to be possible for the first time with a linear range from 0.01 to 0.20 μg mL(-1) and a detection limit of 0.017 μg mL(-1) under model conditions; proof-of-concept is demonstrated in spiked urine.

DOI: 10.1039/c4an00957f

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Cite this paper

@article{Zhang2014GreenES, title={Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1).}, author={Ying Zhang and Wei Zhang and Qing Zhang and Kaiyang Li and Wei Liu and Yong Liu and Craig E. Banks}, journal={The Analyst}, year={2014}, volume={139 21}, pages={5362-6} }