Great strides in the understanding of renal magnesium and calcium reabsorption.

@article{Monnens2000GreatSI,
  title={Great strides in the understanding of renal magnesium and calcium reabsorption.},
  author={Leo Monnens and Patrick G. Starremans and Ren{\'e} J. M. Bindels},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2000},
  volume={15 5},
  pages={
          568-71
        }
}
  • L. Monnens, P. Starremans, R. Bindels
  • Published 2000
  • Medicine
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
M, Gaciong Z, Lao M. Efficiency of preventive treatment of elucidate the anti-apoptotic effects of the aboveglucocorticoid-induced osteoporosis with 25-hydroxyvitamin D3 recommended drugs in human bone and to develop and calcium in kidney transplant patients. Transplant Proc 1996; new, pathophysiology-based rather than empirical 28: 3485–3487 strategies in the treatment of COP. 8. Dequeker J, Van Cleemput J, Declerck K, Mbuyi Muamba JM. Role of alfacalcidiol on bone quality and immunomodulation… Expand
Genetic disorders of magnesium homeostasis
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A clinical and genetic overview of the current insights in different forms of familial hypomagnesemia is given and the putative correlations of the genetic defects with associated electrolyte disturbances are discussed. Expand
[Molecular physiological study of electrolyte transporters in renal tubular epithelial cells].
  • A. Ikari
  • Chemistry, Medicine
  • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
  • 2009
TLDR
It is thought that abnormal transport of electrolytes in renal tubule is involved in lifestyle-related diseases and renal failure, and the phosphorylation of claudin-16 is necessary for its localization on the TJ and claud in Dahl salt-sensitive (DS) hypertensive rats is found. Expand
Partial human genetic deficiency in tissue kallikrein activity and renal calcium handling.
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Results suggest in R53H individuals an increase in Ca reabsorption in the thick ascending limb under baseline conditions that counteracts a distal tubular defect that is revealed by furosemide infusion. Expand
Novel paracellin-1 mutations in 25 families with familial hypomagnesemia with hypercalciuria and nephrocalcinosis.
TLDR
Haplotype analysis strongly suggested a founder effect among patients with FHHNC who originated from Germany or eastern European countries, and hypercalciuria and/or nephrolithiasis were observed in otherwise unaffected family members, indicating a possible role of heterozygous PCLN-1 mutations in yieldinghypercalciuric stone-forming conditions. Expand
Hydrochlorothiazide in CLDN16 mutation.
  • B. Zimmermann, C. Plank, +4 authors J. Dötsch
  • Medicine
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2006
TLDR
It is demonstrated that HCT is effective in reducing hypercalciuria due to CLDN16 mutation on a short-term basis and the efficacy of HCT to attenuate disease progression remains to be elucidated. Expand
Follow-up of five patients with FHHNC due to mutations in the Paracellin-1 gene
TLDR
The clinical course of PCLN-1 mutations as presented in this study is highly variable, ranging from compensated renal failure to end-stage renal failure – as happened in two of the authors' patients. Expand
[Inherited monogenic kidney stone diseases: recent diagnostic and therapeutic advances].
TLDR
Better awareness to the rare monogenic forms of nephrolithiasis and/or nephrocalcinosis should allow early diagnosis and treatment which are needed to prevent or substantially delay progression of end-stage renal disease. Expand
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TLDR
This review summarizes hereditary diseases caused by mutations in genes encoding various proteins operating along the renal tubule or modulating tubular function, which result in derangements in mineral homeostasis or bone disease. Expand
Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes
TLDR
The study suggests that high intake of Mg may be associated with reduced risks of fatty liver disease and prediabetes in those whose Ca intake is less than 1200 mg/d. Expand
Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study.
TLDR
It is hypothesized that polymorphisms in KCNJ1, SLC12A1, and 7 other genes may modify the association between calcium intake and colorectal neoplasia risk and these findings, if confirmed, will be critical for the development of personalized prevention strategies for coloreCTal cancer. Expand
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