Grb2 is required for the development of neointima in response to vascular injury.

@article{Zhang2003Grb2IR,
  title={Grb2 is required for the development of neointima in response to vascular injury.},
  author={Shaosong Zhang and Jie Ren and Mohammad Faisal Khan and Alec M. Cheng and Dana Abendschein and Anthony J. Muslin},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2003},
  volume={23 10},
  pages={1788-93}
}
OBJECTIVE Neointima formation occurs in arteries in response to mechanical or chemical injury and is responsible for substantial morbidity. In this work, the role of the intracellular linker protein Grb2 in the pathogenesis of neointima formation was examined. Grb2 is a critical signaling protein that facilitates the activation of the small GTPase ras by… CONTINUE READING