Grayanotoxin-III Detection and Antioxidant Activity of Mad Honey

@article{Sahin2015GrayanotoxinIIIDA,
  title={Grayanotoxin-III Detection and Antioxidant Activity of Mad Honey},
  author={Huseyin Sahin and Emine Aky{\"u}z Turumtay and Oktay Yıldız and Sevgi Kolaylı},
  journal={International Journal of Food Properties},
  year={2015},
  volume={18},
  pages={2665 - 2674}
}
“Mad honey” is a complex mixture of numerous chemicals produced by honeybees from Rhododendron flowers. Consumption of mad honey leads to diarrhea, perspiration, dizziness, changes in consciousness, syncope, diplopia, as well as blurred vision, hypotension, and bradycardia due to the presence of grayanotoxins (GTXs). Therefore, it is important to detect the level grayanotoxins in mad honey. Besides its toxicity, mad honey also has antioxidant activity. This study was designed to determine the… Expand
Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment
TLDR
The prognosis for mad honey intoxication is very good, and no fatalities have been reported in modern medical literature excluding a few in the 1800s, so the diagnosis, prognosis, and treatment are very good. Expand
Effects of Mad Honey on Some Biochemical Parameters in Rats
TLDR
The use of increasing concentrations of Rhododendron honey was seen as a source of enzymatic symptoms, and the biochemical analysis of the tested parameters showed a significant elevation with increasing concentration of honey. Expand
Investigation of the inhibitory properties of some phenolic standards and bee products against human carbonic anhydrase I and II
TLDR
Investigation of the inhibition effects of various phenolic standards, honey, propolis, and pollen species on human carbonic anhydrase I and II found inhibition was related to total phenolic contents (TFC), and inhibition wasrelated to TFC. Expand
Assessment of phenolic profile of Turkish honeys
ABSTRACT In this study, phenolic profile and antioxidant activity of 60 Turkish honey samples of nineteen different floral origins were evaluated by ultra-performance liquid chromatography withExpand
Determination of histological, immunohistochemical and biochemical effects of acute and chronic grayanotoxin III administration in different doses in rats
TLDR
It was found that dose-dependent acute and chronic effects of GTX-III are different, and this factor should be taken into account in studies to be carried out due to the adverse effects of high doses. Expand
Anti-inflammatory, antioxidant and wound-healing effects of mad honey in streptozotocin-induced diabetic rats
TLDR
The topical use of mad honey improves the healing of diabetic wounds in examined rats and significantly lower MDA levels and TNF-α and MMP-9 expression, and increased antioxidant enzyme activities and IL-10 expression were observed in the mad honey group (Group III) compared with Group I. Expand
CYTOTOXIC AND ANTI-PROLIFERATIVE EFFECTS OF RHODODENDRON PONTICUM L. EXTRACT ON RAT GLIOMA CELL LINE (F98)
The genus Rhododendron has been widely used in traditional medicine. Rhododendron ponticum L. (R. ponticum) contains grayanotoxins with diterpene qualities. The aim of this study was to investigateExpand
Cytotoxic Effects of Rhododendron ponticum L . Extract on Prostate Carcinoma and Adenocarcinoma Cell Line ( DU 145 , PC 3 )
Rhododendron species, having been used in traditional medicine for the treatment of inflammation, pain, cold, asthma, skin and gastro-intestinal disease, are distributed widely around the world. MadExpand
Study on Antioxidant Activity and Amino Acid Analysis of Rapeseed Protein Hydrolysates
Alkaline extraction followed by acid precipitation were employed to extract rapeseed protein and, Alcalase 2.4 L was used to obtain rapeseed protein hydrolysates. Three groups of rapeseed proteinExpand
Non-Acetolysed Pollen Analysis of Mad Honey from the Himalayas, Nepal
Beekeeping practice started a long time ago in Nepal, and nowadays it is gaining momentum as a highly valued and income-generating activity for the local people of the Himalayan region. Five speciesExpand
...
1
2
...

References

SHOWING 1-10 OF 38 REFERENCES
Analysis of grayanatoxin in Rhododendron honey and effect on antioxidant parameters in rats.
TLDR
It has been observed that both Grayanotoxin and high dose Rhododendron honey treatments showed oxidant effect on blood plasma and organ tissues investigated. Expand
Evaluation of antioxidant activity and total phenolics of selected Czech honeys
Abstract Honey serves as a good source of natural antioxidants, which are effective in reducing the risk occurrence of heart disease, cancer, cataracts, different inflammatory processes andExpand
Evaluation of the Phenolic Content, Antiradical, Antioxidant, and Antimicrobial Activity of Different Floral Sources of Honey
TLDR
The honey samples showed the highest antimicrobial activity against some microorganisms, especially Escherichia coli O157:H7, Salmonella typhimurium, Staphylococcus aureus, Listeria monocytogenes, and Proteus mirabilis and Aeromonas hydrophila were the most resistant microorganisms. Expand
Total phenolic content, antiradical, antioxidant and antimicrobial activities of Rhododendron honeys
TLDR
Honey samples obtained from Black Sea Region of Turkey were screened for total phenolic content by the modified Folin–Ciocalteu method, for potential antioxidant activity using phosphomolybdenum assay and by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) method for antiradical activity. Expand
Antioxidant Activity of Artisanal Honey From Tabasco, Mexico
Potential claims for honey, floral variety and their health properties are relevant for small farmers and artisan producers. The antioxidant activity of honey samples from cacao farms, mangrove,Expand
Comparative analysis of antioxidant activity of honey of different floral sources using recently developed polarographic and various spectrophotometric assays
Abstract Hydrogen peroxide scavenging (HPS) activity of honey of different floral sources and its constituents such as predominant honey flavonoids, phenolic acids, amino and organic acids, andExpand
Determination of Chemical Composition, Total Phenolic, Antimicrobial, and Antioxidant Activities of Echinophora tenuifolia Essential Oil
In this study, the antioxidant and antimicrobial activities, total phenolic content, and essential oil composition of Echinophora tenuifolia L. subsp. sibthorpiana were investigated. The antioxidantExpand
Biological activities and chemical composition of three honeys of different types from Anatolia
TLDR
The chestnut flower honey had the highest phenolic content, superoxide radical-scavenging activity and reducing power, while the heterofloral honey sample exhibited the highest peroxynitrite-sc avenging activity. Expand
Evaluation of the antioxidant power of honey, propolis and royal jelly by amperometric flow injection analysis.
TLDR
The applicability of a flow injection system, operating with an amperometric detector, for measurement in rapid and simple way the antioxidant power of honey, propolis and royal jelly is described and a good correlation was found. Expand
Antioxidant activity applying an improved ABTS radical cation decolorization assay.
A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and hydrophilic antioxidants, including flavonoids, hydroxycinnamates,Expand
...
1
2
3
4
...