Gray matter blood flow and volume are reduced in association with white matter hyperintensity lesion burden: a cross-sectional MRI study

@inproceedings{Crane2015GrayMB,
  title={Gray matter blood flow and volume are reduced in association with white matter hyperintensity lesion burden: a cross-sectional MRI study},
  author={David E. Crane and Sandra E. Black and Anoop Ganda and David J. Mikulis and Sean M. Nestor and Manus J. Donahue and Bradley J MacIntosh},
  booktitle={Front. Aging Neurosci.},
  year={2015}
}
Cerebral White Matter Hyperintensities (WMH) are associated with vascular risk factors and age-related cognitive decline. WMH have primarily been associated with global white matter and gray matter (GM) changes and less is known about regional effects in GM. The purpose of this study was to test for an association between WMH and two GM imaging measures: cerebral blood flow (CBF) and voxel-based morphometry (VBM). Twenty-six elderly adults with mild to severe WMH participated in this cross… CONTINUE READING

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