Gray matter abnormalities in opioid-dependent patients: A neuroimaging meta-analysis

  title={Gray matter abnormalities in opioid-dependent patients: A neuroimaging meta-analysis},
  author={Scott C. Wollman and Omar M Alhassoon and Matthew G. Hall and Mark Joseph Stern and Eric J. Connors and Christine L. Kimmel and Kenneth E. Allen and Rick A. Stephan and Joaquim Radu{\`a}},
  journal={The American Journal of Drug and Alcohol Abuse},
  pages={505 - 517}
ABSTRACT Background: Prior research utilizing whole-brain neuroimaging techniques has identified structural differences in gray matter in opioid-dependent individuals. However, the results have been inconsistent. Objectives: The current study meta-analytically examines the neuroimaging findings of studies published before 2016 comparing opioid-dependent individuals to drug-naïve controls. Method: Exhaustive search of five databases yielded 12 studies that met inclusion criteria. Anisotropic… 

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