Gray matter abnormalities associated with duration of untreated psychosis

@article{Lappin2006GrayMA,
  title={Gray matter abnormalities associated with duration of untreated psychosis},
  author={Julia M. Lappin and Kevin D Morgan and Craig Morgan and Gerard Hutchison and Paola Dazzan},
  journal={Schizophrenia Research},
  year={2006},
  volume={83},
  pages={145-153}
}
PURPOSE A long duration of untreated psychosis (DUP) is associated with relatively poor clinical and social outcomes. In order to identify whether an anatomically mediated mechanism may give rise to poorer outcomes, it is important to identify whether a long DUP is associated with greater brain structural abnormalities. METHOD 81 patients with first-episode psychosis (schizophrenia, affective, and other psychoses) were scanned using high resolution Magnetic Resonance Imaging. DUP was defined… CONTINUE READING
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