Gray Matter Changes in Late Life Depression—a Structural MRI Analysis

@article{Andreescu2008GrayMC,
  title={Gray Matter Changes in Late Life Depression—a Structural MRI Analysis},
  author={Carmen Andreescu and Meryl Ann. Butters and Amy E. Begley and Tarek K Rajji and Minjie Wu and Carolyn C. Meltzer and Charles F. Reynolds and H J Aizenstein},
  journal={Neuropsychopharmacology},
  year={2008},
  volume={33},
  pages={2566-2572}
}
Multiple brain morphometric changes have been reported in late-life depression (LLD), mostly in studies comparing volumes of circumscribed brain areas. The aim of our study is to characterize the volumetric changes of multiple gray matter regions in relation to age of onset/duration of illness. We predicted that the association of gray matter volumes with total duration of illness and age of onset would differ depending on whether the region was susceptible to the toxic effects of chronic… CONTINUE READING
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