Graves' Disease.

@article{Smith2016GravesD,
  title={Graves' Disease.},
  author={Terry J. Smith and Laszlo Heged{\"u}s},
  journal={The New England journal of medicine},
  year={2016},
  volume={375 16},
  pages={
          1552-1565
        }
}
Q: What is Graves’ disease? A: Graves’ disease is an autoimmune disease that affects the thyroid. The thyroid is a small gland in the front of the neck. It makes hormones called T3 and T4 that regulate how the body uses energy. Thyroid hormone levels are controlled by the pituitary, which is a pea-sized gland in the brain. It makes thyroid stimulating hormone (TSH), which triggers the thyroid to make thyroid hormone. 
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304 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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304 Citations

Primer on Graves’ Disease: What the Ophthalmologist Should Know and Do

This chapter will discuss the present state of knowledge regarding epidemiology, risk factors and pathophysiology of GD and review diagnosis and management of the disease with a focus on what the ophthalmologist should know and do.

Graves’ disease

The epidemiology, pathophysiology and diagnosis of Graves’ disease are discussed, the need for better therapeutics for its management is highlighted and a number of important advances are on the horizon.

Spectrum of thyroid disease in a single patient: A case of papillary thyroid carcinoma in a patient with Graves' disease and Hashimoto's thyroiditis

A 65‐year‐old man with a history of Hashimoto's thyroiditi on Levothyroxine developed Graves' disease with ocular symptoms and was treated with teprotumumab without improvement. Total thyroidectomy…

Graves’ Disease in Pregnancy: A Systematic Review

Pre- and postpartum planning and the effective management of Graves’ disease in women of childbearing age are necessary to prevent the pathogenesis of Graves' disease during pregnancy.

2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease.

Extrathyroidal Manifestations of Thyroid Disease: Graves Eye Disease.

Flash Pulmonary Edema: A Rare Presentation of Graves’ Disease

A case of a young woman who presented in the emergency room with acute onset of cough with mild hemoptysis and dyspnea at rest and the diagnosis of Graves’ disease in thyrotoxic crisis presenting with flash pulmonary edema is reported.

Graves' Disease Presenting as a Unilateral Breast Mass

It is important to keep a high index of suspicion for thyroid disease as hyperthyroid states may be deceiving in presenting with single organ system involvement.

Immunological Aspects of Graves' Ophthalmopathy

Based on the available medical literature, the immunological mechanism of GO pathogenesis has been summarized and particular attention was paid to the role of orbital fibroblasts and putative autoantigens.

Pathogenesis and Medical Management of Thyroid Eye Disease

Thyroid eye disease (TED) is caused by an inflammatory process involving the orbit and periorbital tissues in the setting of autoimmune thyroiditis. TED has been shown not only to impact visual and…
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