Graphlet-based edge clustering reveals pathogen-interacting proteins

@inproceedings{Solava2012GraphletbasedEC,
  title={Graphlet-based edge clustering reveals pathogen-interacting proteins},
  author={Ryan W. Solava and Ryan P. Michaels and Tijana Milenkovi{\'c}},
  booktitle={Bioinformatics},
  year={2012}
}
MOTIVATION Prediction of protein function from protein interaction networks has received attention in the post-genomic era. A popular strategy has been to cluster the network into functionally coherent groups of proteins and assign the entire cluster with a function based on functions of its annotated members. Traditionally, network research has focused on clustering of nodes. However, clustering of edges may be preferred: nodes belong to multiple functional groups, but clustering of nodes… CONTINUE READING
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