Graphene quantum dots with nitrogen-doped content dependence for highly efficient dual-modality photodynamic antimicrobial therapy and bioimaging.

@article{Kuo2017GrapheneQD,
  title={Graphene quantum dots with nitrogen-doped content dependence for highly efficient dual-modality photodynamic antimicrobial therapy and bioimaging.},
  author={Wen-Shuo Kuo and Hua-han Chen and Shih-Yao Chen and Chia-Yuan Chang and Peikai Chen and Yung-I Hou and Yu-Ting Shao and Hui-Fang Kao and Chih-Li Lilian Hsu and Yi-Chun Chen and Shean-Jen Chen and Shao-gang Wu and Jiu-Yao Wang},
  journal={Biomaterials},
  year={2017},
  volume={120},
  pages={
          185-194
        }
}
Reactive oxygen species is the main contributor to photodynamic therapy. The results of this study show that a nitrogen-doped graphene quantum dot, serving as a photosensitizer, was capable of generating a higher amount of reactive oxygen species than a nitrogen-free graphene quantum dot in photodynamic therapy when photoexcited for only 3 min of 670 nm laser exposure (0.1 W cm-2), indicating highly improved antimicrobial effects. In addition, we found that higher nitrogen-bonding compositions… CONTINUE READING
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