Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid

@article{Kantola1998GrapefruitJG,
  title={Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid},
  author={T. Kantola and K. Kivistö and P. Neuvonen},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1998},
  volume={63}
}
Grapefruit juice increases the bioavailability of several drugs known to be metabolized by CYP3A4. We wanted to investigate a possible interaction of grapefruit juice with lovastatin, a cholesterollowering agent that is partially metabolized by CYP3A4. 
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Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin
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Management of grapefruit-drug interactions.
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Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
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