Corpus ID: 18456926

Grape seed proanthocyanidins extracts promote apolipoprotein A-I mRNA expression in HepG2 cells under experimental sugar and high-sugar conditions.

@article{Zhai2012GrapeSP,
  title={Grape seed proanthocyanidins extracts promote apolipoprotein A-I mRNA expression in HepG2 cells under experimental sugar and high-sugar conditions.},
  author={O. Zhai and N. Zhong and H. Q. Gao and B. Y. Li and B. Jiang},
  journal={European review for medical and pharmacological sciences},
  year={2012},
  volume={16 3},
  pages={
          299-304
        }
}
  • O. Zhai, N. Zhong, +2 authors B. Jiang
  • Published 2012
  • Chemistry, Medicine
  • European review for medical and pharmacological sciences
OBJECTIVES In this study, we investigated the effect of grape seed proanthocyanidins extracts (GSPE), which have been proved to have anti-oxidative and anti-aging functions, on the expression of apoA-L at mRNA level of HepG2 cells in vitro under the experimental conditions of high-sugar and sugar. MATERIALS AND METHODS Cell viability was measured by sulforhodamine B (SRB). The apoA-I mRNA expression was assayed by real-time fluorescence quantitative polymerase chain reaction. Firstly, HepG2… Expand
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