Grape Resveratrol Increases Serum Adiponectin and Downregulates Inflammatory Genes in Peripheral Blood Mononuclear Cells: A Triple-Blind, Placebo-Controlled, One-Year Clinical Trial in Patients with Stable Coronary Artery Disease

@inproceedings{TomCarneiro2012GrapeRI,
  title={Grape Resveratrol Increases Serum Adiponectin and Downregulates Inflammatory Genes in Peripheral Blood Mononuclear Cells: A Triple-Blind, Placebo-Controlled, One-Year Clinical Trial in Patients with Stable Coronary Artery Disease},
  author={Joao Tom{\'e}-Carneiro and Manuel Gonz{\'a}lvez and Mar Larrosa and Mar{\'i}a Josefa Ya{\~n}{\'e}z-Gasc{\'o}n and Francisco J. Garc{\'i}a-Almagro and Jos{\'e} A. Ruiz-Ros and Francisco Tom{\'a}s Barber{\'a}n and Mar{\'i}a-Teresa Garc{\'i}a-Conesa and Juan Carlos Esp{\'i}n},
  booktitle={Cardiovascular Drugs and Therapy},
  year={2012}
}
The grape and wine polyphenol resveratrol exerts cardiovascular benefits but evidence from randomized human clinical trials is very limited. We investigated dose-depending effects of a resveratrol-containing grape supplement on stable patients with coronary artery disease (CAD) treated according to currently accepted guidelines for secondary prevention of cardiovascular disease. In a triple-blind, randomized, placebo-controlled, one-year follow-up, 3-arm pilot clinical trial, 75 stable-CAD… CONTINUE READING
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