Granulopoiesis in childhood aplastic anemia.

  title={Granulopoiesis in childhood aplastic anemia.},
  author={Abdelsalam H. Ragab and Ellen Gilkerson and William M. Crist and Eithne Phelan},
  journal={The Journal of pediatrics},
  volume={88 5},
The soft agar technique was employed to investigate factors involved in the regulation of granulopoiesis in ten children with aplastic anemia. Children with AA had greatly reduced numbers of granulocytic colony-forming cells in their bone marrow and in their peripheral blood when compared to "control" children. Colony-stimulating activity was decreased in… CONTINUE READING