Granulomatosis with polyangiitis (Wegener granulomatosis) as a differential diagnosis of sternal osteomyelitis: the challenges in diagnosis.

@article{Kim2013GranulomatosisWP,
  title={Granulomatosis with polyangiitis (Wegener granulomatosis) as a differential diagnosis of sternal osteomyelitis: the challenges in diagnosis.},
  author={Sang-Dong Kim and Gun-Woo Kim and Tae-Eun Kim and Eun-Jung Nam and Seung-Woo Han},
  journal={Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases},
  year={2013},
  volume={19 8},
  pages={446-8}
}
Although granulomatosis with polyangiitis (GPA) can affect a large number of organ systems and produce a broad spectrum of clinical symptoms, skeletal involvement is very rare, with the exception of facial bone involvement associated with destructive nasal and sinus inflammation. We describe here a 54-year-old man with sternal osteomyelitis and destructive arthritis around the sternoclavicular joint. Despite antibiotics and conventional immunosuppressive treatment, his symptoms deteriorated… CONTINUE READING