Granulocyte transfusions for neutropenic patients with life-threatening infections: a single centre experience in 47 patients, who received 348 granulocyte transfusions.

@article{Ofran2007GranulocyteTF,
  title={Granulocyte transfusions for neutropenic patients with life-threatening infections: a single centre experience in 47 patients, who received 348 granulocyte transfusions.},
  author={Yishai Ofran and Irit Avivi and Arie Oliven and I lana Oren and Tsila Zuckerman and Lilach Bonstein and Jacob M. Rowe and Eldad J Dann},
  journal={Vox sanguinis},
  year={2007},
  volume={93 4},
  pages={363-9}
}
INTRODUCTION The role of granulocyte transfusions (GT) in patients with neutropenia-related infections remains controversial. MATERIALS AND METHODS A retrospective analysis of 47 neutropenic patients, treated with 348 consecutive GTs for life-threatening infections between 1999 and 2004, is presented. RESULTS The only grade III-IV toxicity observed in GT recipients was respiratory deterioration (n = 6, 12.8%). The overall infection-related mortality (IRM) approached 38%. Achievement of a… CONTINUE READING

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