Granulocyte-macrophage colony-stimulating factor responses of oral epithelial cells to Candida albicans.

@article{DongariBagtzoglou2003GranulocytemacrophageCF,
  title={Granulocyte-macrophage colony-stimulating factor responses of oral epithelial cells to Candida albicans.},
  author={A Dongari-Bagtzoglou and Helena Kashleva},
  journal={Oral microbiology and immunology},
  year={2003},
  volume={18 3},
  pages={165-70}
}
Candida albicans is the principal fungal species responsible for oropharyngeal candidiasis, the most frequent opportunistic infection associated with immune deficiencies. Cytokines, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), are important in the generation of effective immunity to C. albicans. The purposes of this investigation were to determine whether C. albicans triggers secretion of GM-CSF by oral epithelial cells in vitro and to investigate mechanisms of host cell… CONTINUE READING