Granulocyte macrophage colony-stimulating factor expression in human herpetic stromal keratitis: implications for the role of neutrophils in HSK.

@article{Duan2007GranulocyteMC,
  title={Granulocyte macrophage colony-stimulating factor expression in human herpetic stromal keratitis: implications for the role of neutrophils in HSK.},
  author={Rui Duan and Lies Remeijer and J. J. C. M. van Dun and Albert D. M. E. Osterhaus and Georges M G M Verjans},
  journal={Investigative ophthalmology & visual science},
  year={2007},
  volume={48 1},
  pages={277-84}
}
PURPOSE Granulocyte macrophage colony-stimulating factor (GM-CSF) is thought to play a key role in chronic inflammatory diseases by governing the survival and function of infiltrating neutrophils. The objective of this study was to determine the putative role of GM-CSF in the pathogenesis of human herpetic stromal keratitis (HSK). METHODS Primary human corneal fibroblast (HCF) cultures and a telomerase-immortalized human corneal epithelial (HCE) cell line representative of native HCE were… CONTINUE READING