Granulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line.

Abstract

Nitric oxide (NO) produced by skin dendritic cells and keratinocytes plays an important role in skin physiology, growth and remodelling. Nitric oxide is also involved in skin inflammatory processes and in modulating antigen presentation (either enhancing or suppressing it). In this study, we found that GM-CSF stimulates the expression of the inducible… (More)

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@article{Cruz2001GranulocytemacrophageCF, title={Granulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line.}, author={Maria Teresa Cruz and C{\'a}tia Duarte and Margarida Gonçalo and Arnaldo J C Figueiredo and Ars{\'e}lio Pato Carvalho and Mar{\'i}a Celeste Lopes}, journal={Immunology and cell biology}, year={2001}, volume={79 6}, pages={590-6} }