Granulocyte colony-stimulating factor to prevent dose-limiting neutropenia in non-Hodgkin's lymphoma: a randomized controlled trial.

@article{Pettengell1992GranulocyteCF,
  title={Granulocyte colony-stimulating factor to prevent dose-limiting neutropenia in non-Hodgkin's lymphoma: a randomized controlled trial.},
  author={Ruth Pettengell and Howard Gurney and John Radford and David P Deakin and Robert James and Peter M. Wilkinson and Khalil Kane and J. Scott Bentley and Dalemari Crowther},
  journal={Blood},
  year={1992},
  volume={80 6},
  pages={1430-6}
}
The effect of granulocyte colony-stimulating factor (G-CSF) on neutropenia, infection, and cytotoxic chemotherapy administration was studied in a randomized trial in patients receiving intensive weekly chemotherapy for non-Hodgkin's lymphoma (NHL). Eighty patients (aged 16 to 71 years) with high-grade NHL (Kiel) of any stage were randomized to receive VAPEC-B chemotherapy alone (39 patients) or with G-CSF administered as a daily subcutaneous dose of 230 micrograms/m2 (41 patients). Prophylactic… CONTINUE READING
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