Granulocyte-colony stimulating factor stimulates immunoreactive endothelin-1 release from cultured bovine endothelial cells.

@article{Namiki1992GranulocytecolonySF,
  title={Granulocyte-colony stimulating factor stimulates immunoreactive endothelin-1 release from cultured bovine endothelial cells.},
  author={Akiyoshi Namiki and Yasunobu Hirata and Masayuki Fukazawa and Masaaki Ishikawa and Masao Moroi and J i Aikawa and Tsuyoshi Yamaguchi and Kiyoshi Machii},
  journal={European journal of pharmacology},
  year={1992},
  volume={227 3},
  pages={339-41}
}
We examined the effect of human recombinant granulocyte-colony stimulating factor (G-CSF) on the release of immunoreactive endothelin-1 (ET-1) from cultured bovine vascular endothelial cells. G-CSF dose dependently (10(-8)-10(-6) M) increased the release of immunoreactive ET-1 as a function of time under a serum-free condition. Coaddition of G-CSF and… CONTINUE READING