Granulocyte colony-stimulating factor promotes behavioral recovery in a mouse model of traumatic brain injury.

Abstract

Hematopoietic growth factors such as granulocyte colony-stimulating factor (G-CSF) represent a novel approach for treatment of traumatic brain injury (TBI). After mild controlled cortical impact (CCI), mice were treated with G-CSF (100 μg/kg) for 3 consecutive days. The primary behavioral endpoint was performance on the radial arm water maze (RAWM… (More)
DOI: 10.1002/jnr.23714

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