Granulocyte colony-stimulating factor increases hepatic sinusoidal perfusion during liver regeneration in mice.

@article{Sidler2008GranulocyteCF,
  title={Granulocyte colony-stimulating factor increases hepatic sinusoidal perfusion during liver regeneration in mice.},
  author={Daniel Sidler and P Studer and Sebastian K{\"u}pper and Beat Gloor and Daniel Candinas and J{\"o}rg Haier and Daniel Inderbitzin},
  journal={Journal of investigative surgery : the official journal of the Academy of Surgical Research},
  year={2008},
  volume={21 2},
  pages={
          57-64
        }
}
Conditioning with granulocyte colony-stimulating factor (G-CSF) promotes liver regeneration in an experimental small-for-size liver remnant mouse model. The mechanisms involved in this extraordinary G-CSF effect are unknown. The aim of this study was to investigate the influence of G-CSF on the hepatic microvasculature in the regenerating liver. The hepatic sinusoidal microvasculature and microarchitecture of the regenerating liver were evaluated by intravital microscopy in mice. Three… CONTINUE READING
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