Granulocyte colony-stimulating factor improves deficient in vitro neutrophil transendothelial migration in patients with advanced liver disease.

@article{Fiuza2002GranulocyteCF,
  title={Granulocyte colony-stimulating factor improves deficient in vitro neutrophil transendothelial migration in patients with advanced liver disease.},
  author={Carmen Fiuza and Magdalena Salcedo and Gerardo Clemente and Jose M. Tellado},
  journal={Clinical and diagnostic laboratory immunology},
  year={2002},
  volume={9 2},
  pages={
          433-9
        }
}
Bacterial infections are frequent complications in patients with liver cirrhosis. Cirrhotic patients present abnormalities in both innate and adaptive immune responses, including a deficient neutrophil recruitment to infected sites. The purpose of this study was to assess neutrophil-endothelium interactions in cirrhotic patients and evaluate the effects of G-CSF on this process. We studied neutrophil adhesion and transendothelial migration in 14 cirrhotic patients and 14 healthy controls. We… CONTINUE READING
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