Granulocyte and granulocyte-macrophage colony-stimulating factors for treatment of neutropenia in glycogen storage disease type Ib.

@article{Schroten1991GranulocyteAG,
  title={Granulocyte and granulocyte-macrophage colony-stimulating factors for treatment of neutropenia in glycogen storage disease type Ib.},
  author={Horst Schroten and Joachim Roesler and Th Breidenbach and Udo Wendel and J{\"o}rn Elsner and Susann Schweitzer and Connie Zeidler and Stefan E. G. Burdach and M-L. Lohmann-Matthes and Volker Wahn},
  journal={The Journal of pediatrics},
  year={1991},
  volume={119 5},
  pages={
          748-54
        }
}
Two children with glycogen storage disease type Ib associated with numerous recurrent bacterial infections as a result of neutropenia and neutrophil dysfunction were treated with recombinant human granulocyte colony-stimulating factor (G-CSF). One of the two patients was previously treated with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF); therapy had to be discontinued because of severe local side effects. Both colony-stimulating factors at dosages of 3 and 8… CONTINUE READING
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