Granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) and granulocyte colony‐stimulating factor (G‐CSF) secretion by adherent monocytes measured by quantitative immunoassays

@article{Sallerfors1992GranulocytemacrophageCF,
  title={Granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) and granulocyte colony‐stimulating factor (G‐CSF) secretion by adherent monocytes measured by quantitative immunoassays},
  author={B. Sallerfors and T. Olofsson},
  journal={European Journal of Haematology},
  year={1992},
  volume={49}
}
Abstract:  The kinetics of GM‐CSF and G‐CSF secretion by purified adherent human monocytes were studied by quantitative immunoassays. Interleukin‐1 (IL‐1); 4–40 ng/ml and E. coli lipopolysaccharide (LPS); 0.1–100 ng/ml, were the most effective stimuli and induced dose‐dependent secretion of both GM‐CSF and G‐CSF. Secretion of newly synthesized CSF was detectable 3–6 hours after stimulation and continued for approximately 24 h. Twenty minutes pulse exposure to LPS was sufficient to induce half… Expand
Granulocyte colony‐stimulating factor (G‐CSF) induces the production of cytokines in vivo
Cytokine‐Mediated Regulation of Granulocyte Colony‐Stimulating Factor Production
p38 MAP kinase and MKK‐1 co‐operate in the generation of GM‐CSF from LPS‐stimulated human monocytes by an NF‐κB‐independent mechanism
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