Granulin-epithelin precursor (GEP) as molecular target for treatment of hepatocellular carcinoma

@inproceedings{Cheung2007GranulinepithelinP,
  title={Granulin-epithelin precursor (GEP) as molecular target for treatment of hepatocellular carcinoma},
  author={Siu Tim Cheung and Jenny C. Y. Ho and Sheung Tat Fan},
  year={2007}
}
B222 Hepatocellular carcinoma (HCC) is the major histological type of primary liver cancer, and is the third leading cancer killer worldwide. The disease is frequently diagnosed at an advanced stage and thus precludes curative surgical treatment. There is no effective therapeutic option for the majority of the HCC patients. A new therapeutic strategy is essential. We (Cancer Res 2002; Mol Biol Cell 2002) and others have reported the genome-wide expression profiles of HCC and their clinical… CONTINUE READING